HIGHLY BRANCHED HK PEPTIDES AS EFFECTIVE CARRIERS OF SIRNA

摘要

The present invention is directed to methods of transfecting cells with siRNA,by contacting a transfection complex with one or more cells, where thetransfection complex includes a transport polymer and siRNA. The transportpolymer may include for example, H3K8b and/or structurally similar compounds.The invention is also directed to such transfection complexes, and tocompositions that include such transfection complexes. The invention isfurther directed to methods of treating patients using the transfectioncomplexes of the present invention.