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DIAGNOSTICS AND THERAPEUTICS FOR DISEASES ASSOCIATED WITH VITAMIN D (1,25-DIHYDROXYVITAMIN D3) RECEPTOR 1 (VDR1)
DIAGNOSTICS AND THERAPEUTICS FOR DISEASES ASSOCIATED WITH VITAMIN D (1,25-DIHYDROXYVITAMIN D3) RECEPTOR 1 (VDR1)
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机译:与维生素D(1,25-二羟基维生素D3)受体1(VDR1)相关的疾病的诊断和治疗
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摘要
The invention provides a human VDR1 which is associated with the infections, cardiovascular diseases, respiratory diseases, dermatological diseases, endocrinological diseases, metabolic diseases, cancer, gastroenterological diseases, inflammation, hematological diseases, muscle skeleton disorders and urological diseases. The invention also provides assays for the identification of compounds useful in the treatment or prevention of infections cardiovascular diseases, respiratory diseases, dermatological diseases, endocrinological deiseases, metabolic diseases, cancer, gastroenterological diseases, inflammation, hematological diseases, muscle skeleton disorders and urological diseases. The invention also features compounds which bind to and/or activate or inhibit the activity of VDR1 as well as pharmaceutical compositions comprising such compounds.
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