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PHARMACEUTICAL COMPOSITION CONTAINING EXTRACTS OF CERVUS NIPPON ANTLERS HAVING GROWTH-STIMULATING ACTIVITIES OF HEMATOPOIETIC STEM CELLS AND MEGAKARYOCYTES
PHARMACEUTICAL COMPOSITION CONTAINING EXTRACTS OF CERVUS NIPPON ANTLERS HAVING GROWTH-STIMULATING ACTIVITIES OF HEMATOPOIETIC STEM CELLS AND MEGAKARYOCYTES
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机译:具造血干细胞和巨核细胞生长刺激活性的鹿颈鹿抗性提取物的药物组合物
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摘要
The present invention relates to a pharmaceutical composition having growth-stimulating effects on hematopoietic stem cells and megakaryocytes, containing a specific extract or Cervus nippon antlers, especially a chloroform extract of Cervus nippon antlers and to a biologically active compound isolated from the extracts of Cervus nippon antlers, to a process for preparing the biologically active compounds and to a pharmaceutical composition containing the biological active compounds. The biologically active compounds have monoacetyl diglyceride structure with various side branches as shown in formula (I) where R1 is 9-octadecenoyl and R2 is hexadecanoyl (KJ-1), or R1 is hexadecanoyl and R2 is 9-octadecenoyl (KJ-2), or R1 is hexadecanoyl and R2 is 9,12-octadecadienoyl (KJ-3), or R1 is hexadecanoyol and R2 is 9,12,15-optadecatrienoyl (KJ-4), or R1 is hexadecanoyl and R2 is 5,8,11,14-eicosatetraenoyl (KJ-5).
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