CFTR AS A COMPONENT OF AN AUTOPHAGY SIGNALING PATHWAY, APPLICATIONS THEREOF TO AUTOPHAGIC DISEASES, AND DETERMINATION OF CYSTIC FIBROSIS AS AN AUTOPHAGIC DISEASE

摘要

The present invention demonstrates that CFTR is a key factor of the autophagy signaling pathway. It further demonstrates that the kinase/CFTR pathways are essential to the maturation stage of autophagy. The different aspects of the present invention involve CFTR, and more particularly the kinase/CFTR pathways, and their various uses and applications as a key component of the autophagy signaling pathway. The present invention further identifies cystic fibrosis as an autophagic disease.