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HMG COENZYME A REDUCTASE INHIBITORS AFFECT THE MITOCHONDRIAL DNA CONTENT OF CELLS
HMG COENZYME A REDUCTASE INHIBITORS AFFECT THE MITOCHONDRIAL DNA CONTENT OF CELLS
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机译:HMG辅酶A还原酶抑制剂影响细胞线粒体DNA含量
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摘要
Statins are widely used for the treatment of high cholesterol levels. In the present invention the effect of statins on mitochondrial nucleic acid and the activation state of mitochondria is used in methods for determining whether a subject is at risk of developing side effects of statin treatment, methods for the treatment of a clinical symptom associated with reduced mitochondrial function. Further provided are kits and the like comprising a means for the detection of mitochondrial nucleic acid, or the activation of a mitochondrion for use in a method mentioned above.
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