SOLIDAGO VIRGA-AUREA VAR. GIGANTEA MIQ. EXTRACT FOR TREATING AND PREVENTING BONE METABOLISM AND DISEASE

摘要

The present invention provides a dietary supplement comprising the extract of Solidago Virgaurea useful pharmaceutical composition, and acceptable food supplements containing them for the prevention and treatment of bone metabolic diseases. ; Solidago Virgaurea extract according to the present invention is the first to 80% methanol in leaves of Solidago Virgaurea stem and then removing impurities from the roots to a powder, washed and freeze-dried at -20 ℃, sample weight 10-fold amount (w / v) of to 24 hours using a filter paper, and then extracted three times. the extract was filtered twice to obtain hayeoseo was concentrated with a rotary vacuum evaporator and lyophilized. ; Solidago Virgaurea extract of the present invention induced more rapidly than the that proliferation and differentiation of osteoblasts by complex action than by a single component in a known good for conventional bone diseases food and the positive control group, and also the growth of the rat in the animal experiments Since the height of the bone mineral density and bone mineral content without toxic effects for an effect that can help proper bone disease treatment and prevention. ; Solidago Virgaurea, methanol extract, osteoblasts, osteoclasts, bone metabolism, osteoporosis, bone disease treatment and prevention