Process for preparing Poly?­glutamic acid from Bacillus Subtilis BS62, and Poly?­glutamic acid prepared from the same

摘要

of the present invention is a natural polymer material from Bacillus subtilis strain poly (gamma-glutamic acid) that manufacture method and from which prepared poly (gamma-glutamic acid) by the present invention according to, and more specifically Bacillus subtilis strain BS62 (KACC 91064) the temperature conditions of 30 to 39 in a culture medium containing L- glutamic acid and glucose by selection culturing aerobically in; And a step of purification; From Bacillus subtilis BS62 comprising the poly (gamma-glutamic acid), the D-type / L-type glutamic acid ratio is 40/60 to 60/40 and prepared according to the method and the manufacturing method of manufacturing a weight-average molecular weight and about 600kDa to 1000kDa, the number-average molecular weight was about 200kDa to 500kDa, poly (gamma-glutamic acid), characterized in that the degree of dispersion is from 3 to 3.5. The features ; in the present invention prepared in accordance with the Bacillus subtilis BS62 poly (gamma-glutamic acid) production process of the poly (gamma-glutamic acid) has the advantage that the mass production, whereby the pharmaceutical, food, in the chemical arts viscosity enhancing agents, coating agents, and emitting material for the manufacture of a sustained-release hydrogel can be useful, and more.