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Method for producing enantiomeric pure profens using the racemization and chiral resolution
Method for producing enantiomeric pure profens using the racemization and chiral resolution
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机译:利用外消旋和手性拆分制备对映体纯脯氨酸的方法
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摘要
The invention racemization to optical resolution reaction using racemization and biocatalysis using a chemical catalyst using a chemical catalyst relates to how to interconnect in a reaction system to produce optically pure forms of pro penryu process and the stability at high temperatures and by a combination of the optical resolution process to exhibit optimum activity using a biological catalyst in the hyperthermophilic enzyme used DKR (Dynamic Kinetic Resolution) process to occur in a single reaction system, the optically pure pro penryu high yield It provides a way to get into production. As described above, and the present invention is full-DKR process is faster than the racemization speed it can be performed at a high temperature by improving the yield and the optical purity of the final product by using a hyperthermophilic enzyme to a biological catalyst, conventional chemical the use of an organic solvent provides a method for producing environmentally friendly Pro penryu to significantly reduce, compared to the process. ; Businesses penryu, chemical catalysts and biological catalysts, enzymes hyperthermophilic
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