MEDICINAL AGENT COMPRISING GLUTATHIONE METABOLISM EFFECTOR ALONG WITH -LIPOIC ACID FOR THERAPY IN KIDNEY TRANSPLANTATION

摘要

FIELD: organic chemistry, medicine, pharmacy.;SUBSTANCE: invention relates to a combined medicinal preparation used in treatment of disturbance of thiol-disulfide status in kidney transplantation that comprises ambroxol as an effector of glutathione metabolism, -lipoic acid and additives. Also, invention relates to using inhibitors of activity of angiotensin-converting enzyme - kaptopril, enalapril and ramipril or ambroxol along with -lipoic acid for preparing a medicinal agent used in treatment of disturbance of thiol-disulfide status in kidney transplantation. Invention provides enhancing effectiveness of treatment.;EFFECT: valuable medicinal property of agent and its enhanced effectiveness.;14 cl, 7 dwg, 7 tbl, 6 ex