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New antibody (which specifically recognizes human thiamine 1) useful for blocking the binding of human Thy-1 at its ligand or for blocking the interaction of tumor cells or immune cells with endothelial cells
New antibody (which specifically recognizes human thiamine 1) useful for blocking the binding of human Thy-1 at its ligand or for blocking the interaction of tumor cells or immune cells with endothelial cells
Antibody (I), which specifically recognizes human thiamine 1 (Thy-1) (CD90), for blocking the binding of human Thy-1 at its ligand, is new. Independent claims are also included for: (1) (I) obtained from hybridoma-cell line with the deposit number of DSM ACC2690; (2) hybridoma-cell line with the deposit number DSM ACC2690; (3) preparation of monoclonal antibodies against human Thy-1 comprising immunising BALB/c mice with human Thy-1, fusing its spleen cells, selecting the antibody producing hybridoma in a selective medium, cloning and far increasing the reactive and specific hybridoma by cultivation, where hybridoma-cell line with the deposit number DSM ACC2690 is used for cultivation and antibody production; (4) immunological test kit comprising at least (I) or a product derived from it; and (5) pharmaceutical preparation comprising (I) or a product derived from it. ACTIVITY : Cytostatic; Antiarthritic; Antiinflammatory; Antipsoriatic; Antirheumatic. No biological data given. MECHANISM OF ACTION : None given.
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