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METHOD FOR PREDICTING PROGNOSIS OF PATIENT SUFFERING FROM COLON CANCER AFTER ADMINISTERING ANTI-CANCER AGENT

机译:预防抗癌剂治疗后结肠癌患者预后的预测方法

摘要

PPROBLEM TO BE SOLVED: To provide a gene cluster for accurately predicting the prognosis of a patient suffering from colon cancer after starting the administration of an anti-cancer agent and to provide a method for predicting the prognosis of the patient suffering from the colon cancer using the gene cluster. PSOLUTION: The gene cluster is used for predicting the prognosis of the patient suffering from the colon cancer and receiving the administration of the anti-cancer agent. The gene cluster is composed of two or more genes selected from genes in positive correlation with the prognosis represented by the following (1) to (8) or genes corresponding thereto and genes in negative correlation with the prognosis represented by (9) to (16) or genes corresponding thereto. The genes are (1) TM4SF6 gene, (2) ADRM1 gene, (3) ITGB4BP gene, (4) FLOT2 gene, (5) PHB gene, (6) GSTM1 gene, (7) BCAP31 gene, (8) STIP1 gene, (9) TRIM8 gene, (10) MST1R gene, (11) TCF12 gene, (12) PDE3B gene, (13) CCNG2 gene, (14) SAT gene, (15) ALOX5 gene and (16) MAN2A2 gene. PCOPYRIGHT: (C)2007,JPO&INPIT
机译:<要解决的问题:提供一种基因簇,用于在开始施用抗癌药后准确预测结肠癌患者的预后,并提供一种预测患有结肠癌的患者的预后的方法。使用基因簇的结肠癌。

解决方案:该基因簇用于预测患有结肠癌的患者的预后并接受抗癌药的治疗。基因簇由选自与以下(1)至(8)表示的预后呈正相关的基因或与之相对应的基因和与(9)至(16)表示的预后负相关的基因中的两个或更多个基因组成。 )或与其相对应的基因。这些基因是(1)TM4SF6基因,(2)ADRM1基因,(3)ITGB4BP基因,(4)FLOT2基因,(5)PHB基因,(6)GSTM1基因,(7)BCAP31基因,(8)STIP1基因,(9)TRIM8基因,(10)MST1R基因,(11)TCF12基因,(12)PDE3B基因,(13)CCNG2基因,(14)SAT基因,(15)ALOX5基因和(16)MAN2A2基因。

版权:(C)2007,日本特许厅&INPIT

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