Quantitative trait locus prognostic for changes in regional adiposity and BMI in Caucasian males

摘要

Caucasian males, but not females, presenting with statistically significant increases of L162V allelic SNP of the PPARα gene, relative to that of wild-type homozygotes, have an increased likelihood of increased regional adiposity (subcutaneous fat) and BMI, and are more likely to develop diseases associated with such changes, such as type 2 diabetes and metabolic syndrome.