首页> 外国专利> Ophthalmic composition comprising an aqueous Carrier Component and an effective amount of a component of Tone, its use in preparing Medicine and use of a component Carrier and an effective amount of a component polianionico for preparing the composition

Ophthalmic composition comprising an aqueous Carrier Component and an effective amount of a component of Tone, its use in preparing Medicine and use of a component Carrier and an effective amount of a component polianionico for preparing the composition

机译:包含水性载体组分和有效量的Tone组分的眼科组合物,其在制备药物中的用途以及组分载体和有效量的polianionico组分在制备组合物中的用途

摘要

Ophthalmic composition Components with compatible solutes and / or polianionocos components, comprising a Carrier and an effective amount of an aqueous Component and a component of Tone, effective when administered to One Eye,To allow a better tolerated an Eye Ocular Surface condition on the ocular surface with Hypertonic relative to an identical composition without the material.The composition has an osmolality of the Order of about 300 to 1000 mosmoles / KH, and comprises at least one component selected from additional compatible SOLUTE components of amino acids zwiterionicos polyol Components and their mixtures.Their use for preparing a Medicament used for treating a human or animal Eye comprising administered to one eye which provides at least a benefit, such as relieve Dry Eye Syndrome, protect against injury and / or adverse effects of Hypertonic cationic species on the Hidden surfaces Ares and / or to facilitate the Recovery of surgeries.Claim 1: an ophthalmic composition characterized in that it comprises: an aqueous Carrier Component and an effective amount of a component of Tone which comprises a material selected from the group consisting of Erythritol: Components and Components and mixtures thereof; inositolXylitol Components and mixtures thereof; components of carnitine and mixtures thereof; a material selected from the group formed by combinations of at least two different agents compatible solutes, a compatible SOLUTE Component and a component in an amount and polianionico Fectiva,Provided that the Hyaluronic acid is not the only polianionico Component; and a polianionico compatible SOLUTE Components and a component in an effective amount.
机译:眼科用组合物具有相容性的溶质和/或polianionocos成分的成分,包括载体和有效量的水性成分和Tone成分,施用于一只眼睛时有效,以更好地耐受眼睛的眼表状况相对于没有该材料的相同组合物,该表面具有高渗性。该组合物的重量克分子渗透压浓度为约300至1000摩尔摩尔/ KH,并且包含至少一种选自氨基酸zwiterionicos多元醇的其他相容性SOLUTE组分的组分及其组分它们在制备用于治疗人或动物眼睛的药物中的用途,包括对一只眼睛给药,该眼睛至少提供一种益处,例如缓解干眼症,保护免受高渗阳离子物质的伤害和/或不利影响。隐藏的表面Ares和/或以利于外科手术的恢复。索赔1:眼科用药其特征在于它包含:含水载体组分和有效量的色调组分,其包含选自赤藓糖醇的材料:组分和组分及其混合物;和肌醇木糖醇成分及其混合物;肉碱成分及其混合物;选自至少两种不同试剂的相容性溶质,相容性SOLUTE组分和一定量的组分和聚对苯二酚Fectiva组成的组中的物质。以及与聚离子可相容的SOLUTE成分和有效量的成分。

著录项

  • 公开/公告号AR052031A1

    专利类型

  • 公开/公告日2007-02-28

    原文格式PDF

  • 申请/专利权人 ALLERGAN INC.;

    申请/专利号AR2005P104802

  • 发明设计人

    申请日2005-11-15

  • 分类号A61K9/08;A61K31/045;A61P27/02;

  • 国家 AR

  • 入库时间 2022-08-21 20:59:40

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