compound or pharmaceutically acceptable salts, solvates, hydrates or prodrugs thereof, composition, methods for treating or preventing a disease or condition, cardiovascular disease, dyslipidemia, hypertension, cancer, inflammation, and impotence in a patient, unit dosage form, and method for identifying a compound useful for treating or preventing a condition in a patient

摘要

"COMPOSITION OR SALTS, SOLVATES, HYDRATES OR PRO-DRUGS OF THIS PHARMACEUTICALLY ACCEPTABLE, COMPOSITION, METHODS TO TREAT OR PREVENT A DISEASE, A CARDIOVASCULAR DISEASE, A DISORDER, HYPERATIA, HYPERATIA, HYPERAID, HYDRACANE , UNIT DOSAGE FORM, AND METHOD FOR IDENTIFYING A USEFUL COMPOUND TO TREAT OR PREVENT A CONDITION IN A PATIENT ". The invention relates to novel imitations of Acyl coenzyme A, compositions comprising ketone compounds and methods useful for treating and preventing cardiovascular disease, dyslipidemia, dysproteinemia and glucose metabolism disorders comprising administering a composition comprising a compound of ketone. Acyl coenzyme A mimics, compositions and methods of the invention are also useful for treating and preventing Alzheimer's disease, Syndrome X, peroxisome proliferator activated receptor-related disorders, septicemia, thrombotic disorders, obesity , pancreatitis, hypertension, kidney disease, cancer, inflammation, bacterial infection and impotence. In certain embodiments, Acyl coenzyme A mimics, compositions and methods of the invention are useful in combination therapy with other therapeutic products, such as hypocholesterolemic and hypoglycemic agents.