首页> 外国专利> antibody, method of detecting a metabolic bone disorder, kit for detecting a metabolic bone disorder, pharmaceutical composition for treating a metabolic bone disorder, and method of screening an effective substance for treating and / or preventing a metabolic bone disorder

antibody, method of detecting a metabolic bone disorder, kit for detecting a metabolic bone disorder, pharmaceutical composition for treating a metabolic bone disorder, and method of screening an effective substance for treating and / or preventing a metabolic bone disorder

机译:抗体,检测代谢性骨疾病的方法,检测代谢性骨疾病的试剂盒,用于治疗代谢性骨疾病的药物组合物以及筛选用于治疗和/或预防代谢性骨疾病的有效物质的方法

摘要

ANTIBODY, METHOD OF DETECTING A METABOL ETABUS DISTURBUS, METHODOLOGICAL BONE DISTURB, KIT OF DETECTING A METABOL EARTHYBUS DISTURB, METHOD OF THE METABOL DISTURBUS detection of bone metabolic disorder by the use of a gene strongly expressed in osteoclasts; a method of screening a compound having an effect of treating and / or preventing bone metabolic disorders; and a medicinal composition for the treatment and / or prevention of bone metabolic disorder. Namely, a method of detecting bone metabolic disorder by using human DC-STAMP gene expression as an indication; a medicinal composition containing Antibody that specifically recognizes human DC-STAMP and has an inhibitory activity of osteoclast formation, etc.
机译:抗体,检测代谢物雌二醇的方法,方法学上的骨干扰物,检测代谢物伯类干扰的试剂盒,通过使用在破骨细胞中强烈表达的基因来检测代谢代谢物的方法;筛选具有治疗和/或预防骨代谢异常作用的化合物的方法;和用于治疗和/或预防骨代谢异常的药物组合物。即,以人DC-STAMP基因的表达为指标的骨代谢异常的检测方法。含有特异性识别人DC-STAMP并具有破骨细胞形成抑制活性的抗体的药物组合物。

著录项

  • 公开/公告号BRPI0507645A

    专利类型

  • 公开/公告日2007-07-10

    原文格式PDF

  • 申请/专利权人 SANKYO COMPANY LIMITED;

    申请/专利号BR2005PI07645

  • 申请日2005-02-09

  • 分类号C12N15/09;A61K39/395;A61K48;A61P;A61P19/08;A61P19/10;A61P29;A61P35;C07K16/28;C12P21/08;C12Q1/68;G01N33/15;G01N33/50;G01N33/53;

  • 国家 BR

  • 入库时间 2022-08-21 20:59:18

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