PREPARATIVE FORMS OF ORAL FORMAL MEMANTINE FORMS WITH IMMEDIATE DELIVERY

摘要

The present invention relates to a solid oral immediate release dosage form containing 1-aminocyclohexanes, preferably memantine or neramexane, and optionally a pharmaceutically acceptable coating, where the active ingredient shows dose proportionality and is released at a dissolution rate of more than about 80% within the first approximately 60 minutes after receipt of the specified form in the environment of use. The dosage form is directly compressed and has a hardness of from about 3 to about 40 Kp, shows an average T from about 2 to about 8 hours with a load of the active ingredient from about 2.5 to about 150 mg. Preparative form allows you to create compositions with proportional doses for the reception once or twice a day, and also to maintain a steady average range of T.