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PROCESS FOR THE PRODUCTION OF AN ENTERAL FORMULA CONTAINING ARACHIDONIC ACID AND /OR DOCOSAHEXAENOIC ACID IN THE FORM OF PHOSPHOLIPIDS AND THE FORMULA OBTAINED BY SAME
PROCESS FOR THE PRODUCTION OF AN ENTERAL FORMULA CONTAINING ARACHIDONIC ACID AND /OR DOCOSAHEXAENOIC ACID IN THE FORM OF PHOSPHOLIPIDS AND THE FORMULA OBTAINED BY SAME
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机译:制备含有磷脂形式的花生四烯酸和/或二十二碳六烯酸的肠内制剂的方法和相同的配方
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摘要
Enteral formulas that contain long-chain polyunsaturated fatty acids (PUFAs), e.g. arachidonic acid (AA) and docosahexaenoic acid (DHA) essentially free of cholesterol, and a process for making such enteral compositions are described. More particularly, the invention relates to methods for reducing the incidence of necrotizing enterocolitis by administering compositions which provide n-6 and n-3 long chain PUFAs; phospholipids and/or choline. Compositions from egg yolk lipids are presently preferred as they contain n-6 and n-3 long chain PUFAs and are predominantly in a phosphtidylcholine form. This is believed to provide a synergistic effect. Also disclosed is a process of making such a composition that provides improved organoleptic and stability properties.
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