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A process for grinding in the production of finely milled medicinal substances.
A process for grinding in the production of finely milled medicinal substances.
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机译:一种用于生产精细研磨的药用物质的研磨方法。
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摘要
The present invention is a method of milling materials to form a fine powder with a median particle size below 10 micrometer which is suitable for inhalation and which has substantially no amorphous content generated during milling. The method is particularly suitable for milling materials which are soft. The method comprises milling the material in a fluid energy mill at reduced temperature using helium, or helium mixed with another gas, as milling fluid. Temperatures of -30 DEG C or less are used.
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