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TREATMENT REGIMEN FOR N-MYC, C-MYC, AND L-MYC AMPLIFIED AND OVEREXPRESSED TUMORS
TREATMENT REGIMEN FOR N-MYC, C-MYC, AND L-MYC AMPLIFIED AND OVEREXPRESSED TUMORS
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机译:N-MYC,C-MYC和L-MYC扩增和过表达的肿瘤的治疗方案
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摘要
The present invention relates to methods and compositions for treating diseases. More specifically, the present invention relates to the administration of multiple drugs as part of a treatment of disease. Specific embodiments of the invention relate to a treatment regimen for neuroblastomas and other N-MYC, c-MYC, and L-MYC amplified and overexpressed tumors, comprising administering multiple therapeutic compounds like DFMO, SAM486A, a verinoid and a cytotoxic drug and placing the patient on a low polyamine diet and/or providing the patient with a polyamine limiting dietary supplement.
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