首页> 外国专利> COMPOSITIONS METHODS AND SYSTEMS FOR PULMONARY DELIVERY OF RECOMBINANT HUMAN INTERFERON ALPHA-2B AND OTHER THERAPEUTIC PROTEINS

COMPOSITIONS METHODS AND SYSTEMS FOR PULMONARY DELIVERY OF RECOMBINANT HUMAN INTERFERON ALPHA-2B AND OTHER THERAPEUTIC PROTEINS

机译:重组人干扰素α-2B和其他治疗性蛋白质肺传递的组成方法和系统

摘要

Stable aqueous formulations which are free of products derived from human or animal origin and which maintain high biological activity and high chemical and physical stability of alpha-type interferon, and proteins in general, for an extended period of time. Methods of producing stable aerosol formulations of the same for delivery to the lungs are also provided, as well as systems and methods of delivering the formulations to the lungs for systemic absorption.
机译:稳定的水性制剂,其不含源自人或动物的产物,并在较长的时间内保持高生物活性以及α型干扰素和蛋白质的高化学和物理稳定性。还提供了产生稳定的气雾剂制剂以输送到肺部的方法,以及提供了将气雾剂制剂输送到肺部以进行全身吸收的系统和方法。

著录项

  • 公开/公告号EP1786395A1

    专利类型

  • 公开/公告日2007-05-23

    原文格式PDF

  • 申请/专利权人 ARADIGM CORPORATION;

    申请/专利号EP20050788834

  • 发明设计人 BALWANI GUL P.;BOYD BROOKS;WHATLEY JOHN;

    申请日2005-08-23

  • 分类号A61K9;A61K9/12;A61K38/21;

  • 国家 EP

  • 入库时间 2022-08-21 20:44:04

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