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TUMOR-HOMING CELLS ENGINEERED TO PRODUCE TUMOR NECROSIS FACTOR-RELATED APOPTOSIS-INDUCING LIGAND (TRAIL) BY ADENOVIRAL-MEDIATED GENE TRANSFER
TUMOR-HOMING CELLS ENGINEERED TO PRODUCE TUMOR NECROSIS FACTOR-RELATED APOPTOSIS-INDUCING LIGAND (TRAIL) BY ADENOVIRAL-MEDIATED GENE TRANSFER
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机译:腺病毒介导的基因转移诱导人肿瘤细胞产生肿瘤坏死因子相关的凋亡诱导配体
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摘要
The invention refers to tumor-homing cells expressing the tumor necrosis factor-related apoptosis inducing ligand (TRIAL), particularly to CD34+ and NK cells transduced with adenoviral vectors coding for TRIAL. The cells of the invention are useful for the intravenous treatment of tumors, particularly of lymphoma.
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