MANUFACTURING METHOD OF DEXIBUPROFEN PARTICLE FOR SUSPENSION AND DEXIBUPROFEN SUSPENSION

摘要

The present invention showed an antipyretic analgesic efficacy and fewer side effects are excellent optical isomer Dexibuprofen (Dexibuprofen) the present invention relates to a process for preparing a suspension and the suspension solution by using a raw material, and more particularly to a method of preparing a suspension solution or a uniform deposition Dexibuprofen having a quality as to not undergo precipitation even when stored for a long time relates to. In the present invention, in order to dissolve them Dexibuprofen and Dietmar agent (detergent) and then placed in a Dexibuprofen by Dietmar agent in a ratio of 1: 0.1-1 temperature 50-80 am pro deck with a pen step , purified water is injected into the stirring solution created in the step Dexibuprofen particles to precipitate recrystallized from a recrystallization step and precipitated Dexibuprofen particles were washed with distilled water and then recrystallized particles to precipitate by using a high-speed centrifuge method of producing Dexibuprofen suspension comprising the steps of: obtaining a raw material and suspended in an aqueous solution using a sucrose prepared Dexibuprofen suspension material (sucrose) by the method described above, to which a sweetener, mating agents, coloring and provides a pH adjusting agent, Dexibuprofen suspensions of the manufacturing method comprising the step of adding a preservative, and agar.