A cell derived from a mammalian cell producing a sialylated glycoprotein and CMP-sialic acid transporter and a method of producing a glycoprotein having reduced N-glycolylneuraminic acid and enhanced N-acetylylneuraminic acid content

摘要

The present invention expressing a protein derived from mammalian CMP-SAT and sialylated sugar level to a higher level than the intrinsic cells and decreased the amount of N- glycolic acid by him rilnyu suramin and provides a method for producing a glycoprotein sialic rilhwa content is increased of N- acetylneuraminic acid .