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UTILIZATION OF 2-HYDROXY-4-TRIFLUOROMETHYLBENZOIC ACID DERIVATIVES AS INHIBITORS OF THE ACTIVATION OF THE NUCLEAR TRANSCRIPTION FACTORS NF-?B
UTILIZATION OF 2-HYDROXY-4-TRIFLUOROMETHYLBENZOIC ACID DERIVATIVES AS INHIBITORS OF THE ACTIVATION OF THE NUCLEAR TRANSCRIPTION FACTORS NF-?B
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机译:利用2-羟基-4-三氟苯甲基苯甲酸衍生物作为核转录因子NF-κB活化的抑制剂
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摘要
The invention relates to the use of 2-hydroxy-4-trifluoromethylbenzoic acid derivatives as inhibitors of the activation of the nuclear transcription factor NF- kappa B. The invention also relates to the utilization of 2-hydroxy-4-trifluoromethylbenzoic acid derivatives for the preparation of medicaments to treat or prevent of pathologies associated to the activation of NF- kappa B and/or the expression of genes which are dependent on or regulated by, at least partially, NF- kappa B in mammals, including humans. IMAGE
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