New phosphorous compound useful as ligand in catalyst for e.g. hydroformylation-, hydrocyanation-, carbonylation-, hydroacylation-, hydroamination- and hydro esterification reactions

摘要

Phosphorous compound (I) is new. Phosphorous compound of formula (I) is new. Y1bivalent bridge group with bridge atoms between the flanking bonds; Ra, Rb : (cyclo)alkyl, heterocycloalkyl or (het)aryl (where alkyl is substituted by 1-5 (hetero)cycloalkyl, (het)aryl,(cyclo)alkoxy, heterocycloalkoxy, (het)aryloxy, OH, SH, polyalkyleneoxide, polyalkylene imine, COOH, carboxylate, SO3H, sulfonate, NE1E2, NE1E2E3X-, halo, NO2, acyl or CN), where (hetero)cycloalkyl- and (het)aryl are substituted with 1-5 alkyl; or RaRb+P+X1X25-8 membered heterocycle, optionally substituted with 1-3 (hetero)cycloalkyl or (het)aryl, where heterocycle and the substituted group consists of 1-4 of (cyclo)alkyl, heterocycloalkyl, (het)aryl, OH, SH, polyalkylene oxide, polyalkylene imine, alkoxy, halo, COOH, carboxylate, SO3H, sulfonate, NE4E5, NE4E5E6X-, NO2, alkoxycarbonyl, acyl or CN; E1-E8H, (cyclo)alkyl or aryl; X-anion; Ry : peptide group comprising at least two amino acid units; X1, X2O, S, SiRcRd or NRe; Z : NR9 or CR9R10; Rc, Rd, Re : H, (cyclo)alkyl, heterocycloalkyl or (het)aryl; R1-R10H, (cyclo)alkyl, heterocycloalkyl, (het)aryl, OH, SH, polyalkylene oxide, polyalkylene imine, alkoxy, halo, SO3H, sulfonate, NE7E8, alkylene-NE7E8, CF3, NO2, alkoxycarbonyl, carboxyl, acyl or CN; or two adjacent groups of R1, R2, R4, R6, R8, R9 (for a bonding portion of double bond between the ring atoms) : six membered ring exhibiting a maximum of three non-cumulative double bonds; and a, b, c : 0 or 1. Independent claims are also included for: (1) a catalyst comprising at least a complex having a transition metal and (I) as ligand; (2) a method for hydroformylating a compound containing at least an ethylenic unsaturated double bond comprising reacting the ethylenic unsaturated double bond with carbon monoxide and hydrogen in the presence of the catalyst; and (3) a method for the preparation of chiral compounds comprising reacting the prochiral compound containing at least an ethylenic unsaturated double bond with a substrate in the presence of a chiral catalyst. [Image].