SOMATIC STEM CELL OF LIVING BODY HAVING DIFFERENTIATION INDUCING CAPABILITY TO OVARIAN GRANULOSA CELL OR OVARIAN THECA CELL

摘要

PPROBLEM TO BE SOLVED: To provide a method for establishing a somatic stem cell of a living body capable of inducing the differentiation to ovarian granulosa cell and ovarian theca cell and controlling the differentiation induction of the somatic stem cell of a living body to ovarian granulosa cell and ovarian theca cell. PSOLUTION: The invention provides a somatic stem cell of a living body differentiating to ovarian granulosa cell and ovarian theca cell by collecting from a mammalian, subculturing in a serum-free or low serum content medium for one to eight generations and inducing the expression of a transcription factor Steroidogenic Factor-1, an ovarian granulosa cell and an ovarian theca cell produced by the differentiation, a cell therapeutic agent containing the cells, a method for producing the same, a cell producing the same, and a method for searching a factor inducing the differentiation to the cells. PCOPYRIGHT: (C)2009,JPO&INPIT