Pharmaceutical formulation containing 17-allylamino-17-demethoxygeldanamycin

摘要

A pharmaceutical formulation comprising 17-AAG in an amount from about 1 mg/mL to about 5 mg/mL dissolved in a vehicle comprising (i) a first component that is an aprotic, polar solvent in an amount between about 0.1 and about 10 volume %; and, (ii) a second component that is an aqueous mixture comprising between about 5.0 and about 55.0 volume % long chain triglycerides, in an amount between about 90.0 and 99.9 volume %.