首页> 外国专利> Of the patient to long-acting beta-2 agonist treatment by analyzing polymorphisms in the beta2-adrenergic receptor gene and to identify the patient as a candidate for the treatment with long-acting beta agonist Method for predicting the response

Of the patient to long-acting beta-2 agonist treatment by analyzing polymorphisms in the beta2-adrenergic receptor gene and to identify the patient as a candidate for the treatment with long-acting beta agonist Method for predicting the response

机译:通过分析β2-肾上腺素能受体基因中的多态性,使患者接受长效β-2激动剂治疗,并确定患者为长效β激动剂治疗的候选对象预测反应的方法

摘要

Comprising identifying the presence or absence of a haplotype at least one C in the beta2-adrenergic receptor gene and that isolating a biological sample from the patient, the present invention is a long-acting beta agonist relates to a method for identifying a patient as a candidate for the treatment of. The presence of haplotype C one, indicates that the patient is a good candidate for the treatment at least in the patient samples. For example, the patient respiratory diseases, obstructive airway disease, and preferably may have asthma, COPD or most preferably. The present invention relates to a method for predicting the response of asthmatic patients to long-acting beta-2 agonist therapy comprising detecting polymorphisms in the beta2-adrenergic receptor gene.
机译:包括鉴定β2-肾上腺素能受体基因中至少一个C的单倍型的存在或不存在以及从患者中分离生物样品,本发明是一种长效β激动剂,其用于鉴定患者为β-受体激动剂。候选人的治疗。单倍型C 1的存在表明该患者至少在患者样品中是治疗的良好候选人。例如,患者的呼吸系统疾病,阻塞性气道疾病,并且优选可以患有哮喘,COPD或最优选。本发明涉及预测哮喘患者对长效β2激动剂疗法的反应的方法,该方法包括检测β2肾上腺素能受体基因中的多态性。

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