Equipment and perfusion system for automatic multi-channel patch-clamp recordings method using the inside-out whole-cell configuration

摘要

In order to study the effect of the ion channel migration of various chemical substances, is to provide a method and high-throughput patch clamp measurement system. Patch clamp configuration of one or more established, each containing cells in close contact with the pipette. Pipette is attached to the pipette fixture. Pipette fixture and as in the interior of the well each cell, I moved relative to, a plate made from one or more wells. I measures the electrical properties of the cell.