Electrochemistry activity ligands for arrangement unique two these chain nuclear acid molecular detection

摘要

As for purpose of this invention, it is to offer the chemical compound where the electrochemistry signal anti- noise ratio in electrochemistry detecting (signal-to-noise ratio) it is possible, as a result, detection sensitivity (precision) to make low, it is possible, makes the quantitative measurement of the super minute nuclear acid molecule possible, connects to the base arrangement of the double chain nuclear acid molecule uniquely to improve largely. As for this invention, the ferrocene compound which is displayed with general formula (i): [Conversion 1] (i) (in general formula (i), A is ferrocene content linker or ferrocene -1,1'- iru of two value, R₂ shows the hydrogen atom or alkyl, n and m show optional natural number, V and X connection part the pyrrole imidazole polyamide (PIPA) is), it consists of the said ferrocene compound electrochemistry activity relates to arrangement unique two these chain nuclear acid molecular methods of detection, and includes the said ligand the electrochemistry detection device or the instrument which use ligands and the said ligand for arrangement unique two these chain nuclear acid molecular detection.