compound or a pharmaceutically acceptable salt thereof, pharmaceutical composition, methods for inhibiting the histamine h3 receptor in a mammal, for treating or preventing a nervous system disorder or other disorder associated with the histamine h3 receptor, for treating or preventing obesity, for treating or preventing a disorder or disease, and using a compound or a salt thereof

摘要

COMPOUND OR PHARMACEUTICALLY ACCEPTABLE SALT OF THE SAME, PHARMACEUTICAL COMPOSITION, METHODS FOR INHIBITING HISTAMINE H3 RECEPTOR IN A MAMMFERUS, FOR TREATMENT OR PREVENTION OF A NERVOUS OR RECEIVED HAZARD DISTURBATION OR OTHER FOR THE TREATMENT OR PREVENTION OF DISORDER OR DISEASE AND USE OF A COMPOUND OR SALT THEREOF. The present invention describes novel compounds of Formula I or pharmaceutically acceptable salts thereof, which have histamine H3 receptor antagonist or inverse agonist activity, as well as methods for preparing such compounds. In another embodiment, the invention describes pharmaceutical compositions comprising compounds of Formula I, as well as methods of using these compositions to treat obesity, cognitive impairments, narcolepsy and other histamine H3 receptor-related diseases.