compound, pharmaceutical composition, and uses of an effective amount of a 3-phosphoindol compound or pharmaceutically acceptable salt, prodrug, stereoisomer, tautomer, n-oxide or quaternary amine thereof and an anti-HIV effective treatment amount. a compound of 3-phosphoindole or pharmaceutically acceptable salt, prodrug, stereoisomer, tautomer, n-oxide or quaternary amine thereof

摘要

COMPOUND, PHARMACEUTICAL COMPOSITION, AND USES OF AN EFFICIENT AMOUNT OF A COMPOSITE 3-PHOSFOINDOL OR SALT, PRODUCT, STEREO, STEREO, NUTHIDE OR PHARMACEUTICALLY AMENDED QUARTERLY AMENDED AMENDMENT A COMPOSITE OF 3-PHOSFOINDOL OR SALT, PRODUCT, STEREO - ISEMER, TAUTEMERUM, N-OXIDE OR PHARMACEUTICALLY ACCEPTABLE QUARTERLY AMINE OF THE SAME CROSS REFERENCE TO THIS APPLICATION 611,061, filed September 16, 2005, 60 / 711,445 filed August 25, 2005 and 60 / 711,565 filed August 26, 2005, all entitled "Phosphoindols as HIV Inhibitors." FIELD OF THE INVENTION The present invention provides novel human immunodeficiency virus (HIV) reverse transcriptase inhibitor compounds and their pharmaceutically acceptable salts, prodrugs, analogs and derivatives. Also included are methods of using these compounds for the prophylaxis and treatment of HIV and AIDS infection and pharmaceutical compositions containing the compounds. BACKGROUND OF THE INVENTION Numerous compounds have been synthesized to combat the human immunodeficiency virus (HIV) as it was discovered to be the etiological cause of acquired immunodeficiency syndrome (AIDS) in 1983. A focal point of AIDS research efforts has been and continues to be. the development of human immunodeficiency virus (HIV-1) reverse transcriptase inhibitors, the enzyme responsible for transcription.