首页> 外国专利> method for the treatment, inhibition of progression or eradication of polycystic kidney disease in a mammal in need thereof; product; use of a tace inhibiting compound; pharmaceutical composition for the treatment, inhibition of progression or eradication of polycystic kidney disease in a mammal

method for the treatment, inhibition of progression or eradication of polycystic kidney disease in a mammal in need thereof; product; use of a tace inhibiting compound; pharmaceutical composition for the treatment, inhibition of progression or eradication of polycystic kidney disease in a mammal

机译:在有需要的哺乳动物中治疗,抑制多囊肾疾病的进展或根除的方法;产品;使用抑制排卵的化合物;用于治疗,抑制哺乳动物多囊肾疾病的进展或消除的药物组合物

摘要

METHOD FOR TREATMENT, INHIBITION OF PROGRESSION OR ERADICATION OF POLYTICALLIC KIDNEY DISEASE IN A MAMMER NEEDED BY IT; PRODUCT; USE OF A TACE INHIBITOR COMPOUND; PHARMACEUTICAL COMPOSITION FOR THE TREATMENT, INHIBITION OF PROGRESSION OR ERADICATION OF POLYTICAL KIDNEY DISEASE IN A MAMMER. The present invention provides a method for treating, inhibiting the progression, or eradicating polycystic kidney disease in a patient in need thereof which comprises providing said patient with an effective amount of a TACE inhibitor compound in combination. with an effective amount of a Src kinase inhibitor, a HER-2 kinase inhibitor, or a combination of Src and HER-2 inhibitor.
机译:在其需要的母亲中治疗,抑制多发性肾病的进展或根除的方法;产品;使用止痛药化合物;用于治疗,预防或预防多胺肾病的药物组合物。本发明提供了一种在有需要的患者中治疗,抑制其进展或根除多囊肾疾病的方法,该方法包括向所述患者提供有效量的TACE抑制剂化合物的组合。含有有效量的Src激酶抑制剂,HER-2激酶抑制剂或Src和HER-2抑制剂的组合。

著录项

  • 公开/公告号BRPI0516533A

    专利类型

  • 公开/公告日2008-09-09

    原文格式PDF

  • 申请/专利权人 WYETH;

    申请/专利号BR2005PI16533

  • 发明设计人 PHILIP FROST;

    申请日2005-10-07

  • 分类号A61K31/18;A61K31/47;A61K31/54;A61K31/5513;A61K45/06;A61P35;

  • 国家 BR

  • 入库时间 2022-08-21 20:08:42

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