method of obtaining substituted cyclohexanone penta-1,4-dien-3-ones and derivatives having antitumor and antiparasitic properties, process for preparing 1,5-bis- (aryl) -penta-1,4-dien-3-ones alkylated and acylated, process for preparing substituted 4-nitro-3,5-diaryl-cyclohexanones, process for preparing substituted 2,6-dibenzylidene-4-nitro-3,5-diaryl-cyclohexanones, process for preparing a mixture of quantities (1,5-bis (4-hydroxy-3-methoxy-phenyl) penta-1,4-dien-3-one) and (1,5-bis (3-methoxy-4-acetoxy-phenyl) penta-1,4-dien-3-one), compounds and their uses, pharmaceutical composition, therapeutic method for cancer treatment and synergistic composition

摘要

METHODS OF OBTAINING PENTA-1,4-DIEN-3-ONAS AND CYCLEEXANONES SUBSTITUTED AND DERIVATIVE WITH ANTI-TUMOR AND ANTI-PARASITY PROPERTIES, PROCESS FOR PREPARING 1,5-BIS- (ARYL) -PENTA-1, 4-DIEN-1 Alkylated and acylated, process for preparing substituted 4-nitro-3,5-dialyl-cyclohexanones, process for preparing 2,6-dibenzylidene-4-nitro-3,5-dialyl-cyclohexanones to be prepared A MIXTURE FORMED BY CERTAIN QUANTITIES OF THE COMPOUNDS (1,5-BIS (4-IDROXY-3-METOXY-PHENYL) PENTA-1,4-DIEN-3-ONA) AND (1,5-BIS-3-METYXY-4) PETHYL-PHENYL) PENTA-1,4-DIEN-3-ONA), COMPOUNDS AND THEIR USES, PHARMACEUTICAL COMPOSITION, THERAPEUTIC TREATMENT METHOD AND SYNERGIC COMPOSITION The present invention relates to novel penta-1 derivatives. - dien-3-ones, as well as their obtaining processes. These compounds have strong antitumor activity and outstanding antiparasitic action, are practically non-toxic in laboratory tests and also in histopathological studies. The present invention further relates to a pharmaceutical composition comprising said compounds, method of treating cancers and parasites.