process for obtaining euterpe oleracea (açaì) fruit and stone clusters process for obtaining hydroalcoholic extracts from the cleavages; process of obtaining lyophilisate and / or spray dryer of the hydroalcoholic extract; pharmaceutical compositions containing the lyophilisates and / or spray dryers of said extracts and therapeutic use of the compositions as a vasodilator in the treatment of ischemic, vaso-spastic and arterial hypertension syndromes

摘要

PROCESS FOR OBTAINING EUTERPE OLERACEA FRUIT AND LEAF DECOTS (ACAI) PROCESS FOR OBTAINING HYDRO-ALCOHOLIC EXTRACTS FROM DECOTS; PROCESS FOR OBTAINING HYDRO-ALCOHOL EXTRACT LYOPHILIZED AND / OR SPRAY DRYER; PHARMACEUTICAL COMPOSITIONS CONTAINING THE LYOPHILIZED AND / OR SPRAY DRYER OF EXTRACTS AND THERAPEUTIC USE OF COMPOSITIONS AS A VASODILATOR IN THE TREATMENT OF ISCHEMICAL, VASPASTIC AND HYPERTERIAL SYMPTOMS. This invention is a process for obtaining, by evaporation of alcohol at low pressure, a hydroalcoholic extract obtained from fruits and seeds of the species Euterpe oleracea; process for obtaining a dry residue by lyophilization or a similar method (spray-dryer) obtained from the alcohol-free concentrate; Pharmaceutical compositions containing the dry residue and therapeutic use of the compositions in the prevention and treatment of vaso-spastic, ischemic diseases and hypertension. The dry residue, when studied pharmacodynamically, induced a significant vasodilatory effect on the rat mesenteric vascular bed.