Isolated Antibody or Functional Fragments with Ability To Neutralize HIV strains that encodes; Nucleic Acid; vector and host Cell comprising Said Nucleic Acid method to produce;An Antibody of the Antibody for the immediate treatment; use

摘要

The present application relates to novel human antibodies capable of binding specifically to the R7V epitope of HIV. These antibodies have all human CDR and are capable of specifically neutralizing all strains of HIV, including escape mutants. These antibodies are useful for the treatment of HIV infection, especially in patients in failure of HAART.