首页> 外国专利> A PROCESS FOR THE PREPARATION OF A NOVEL ANTIDIABETIC FORMULATION FROM HUMBOLDTIA DECURRENS.

A PROCESS FOR THE PREPARATION OF A NOVEL ANTIDIABETIC FORMULATION FROM HUMBOLDTIA DECURRENS.

机译:从洪伯氏菌中制备新的抗糖尿病制剂的方法。

摘要

A process for the preparation of a novel antidiabetic formula¬tion comprising root extract of Humboldtia decurrens mixed with conventional pharmaceutical additives such as solid or liquid diluents, exicipients stabilisers and effective at a dose of 1 g root extract per Kg body weight of diabetic animal, which comprises griding the dried root nodules of Humboldtia decurrens to fine powder, extracting the said powder with a non-polar organic solvent for a period ranging from 20-24 hrs at a temperature in the range of 60-80° C, optionally refluxinc with an organic solvent for a period of 15 to 20 hrs., follow¬ed by evaporating the solvent to get the residue, then crys¬tallising the said residue using lower aliphatic alcohol to get a white powder and mixing the s^id white powder with conventional pharmaceutically accepted additives such as herein described.
机译:一种制备新的抗糖尿病制剂的方法,该方法包括将延白草的根提取物与常规药物添加剂(例如固体或液体稀释剂,赋形剂稳定剂)混合,并以每千克糖尿病动物体重1 g根提取物的剂量有效,该方法包括将腐殖质干燥的根瘤网格化成细粉,用非极性有机溶剂在60-80°C的温度下于20-24小时内萃取所述粉末,并可选地进行回流。在有机溶剂中干燥15至20小时,然后蒸发溶剂得到残留物,然后使用低级脂肪醇将所述残留物结晶得到白色粉末,然后将白色固体粉末与常规的药学上可接受的添加剂,例如本文所述。

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