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Antigen arrays presenting IL-5, IL-13 or eotaxin for treatment of allergic eosinophilic diseases
Antigen arrays presenting IL-5, IL-13 or eotaxin for treatment of allergic eosinophilic diseases
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机译:呈现IL-5,IL-13或嗜酸性粒细胞趋化因子的抗原阵列,用于治疗过敏性嗜酸性粒细胞疾病
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摘要
Provided is a composition comprising a virus-like particle and at least one antigen or antigenic determinant, wherein said antigen or said antigenic determinant is a protein or peptide of IL-5, IL-I3 or eotaxin, and wherein said at least one antigen or antigenic determinant is bound to said virus-like particle. Further provided are such compositions comprising recombinant proteins or protein fragments from various human viruses, composition assembling to specific RNA phages, compositions comprising specific antigenic amino acid sequences. Further provided are corresponding pharmaceutical compositions and vaccines and methods of producing them.
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