peptidic structures and their use in the diagnosis of herpes simplex virus type 2.

摘要

peptidic structure presented in multiple forms comprising multiple branches, each containing a peptide, based on a core the structure having the formula (1): [(X1) p - sequence 16aa - (X2) q - Sp] n - core wherein: (i) "sequence of 16 aa" represents a sequence Glu Glu Phe Glu Gly Ala Gly Asp Gly Glu Pro Pro Glu Asp Asp Asp (ii) X1 and X2, which may be identical or different, represent 1 to 6 amino acid residues may be the same or different and which do not interfere with the peptide's ability to bind to antibodies HSV-2; (Iii) p is 0 or 1 and q is 0 or 1; (Iv) Sp represents the spacer group; (V) n is at least 4; and (vi) the spacer groups extend outwardly of the core and the bond between the core and the spacer groups may be chemical or physical.