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Methods of constructing biodiverse gene fragment libraries and biological modulators isolated therefrom
Methods of constructing biodiverse gene fragment libraries and biological modulators isolated therefrom
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机译:构建生物多样性基因片段文库的方法和从中分离的生物调节剂
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摘要
The present invention provides a gene fragment expression library comprising a plurality of different nucleotide sequences derived from biodiverse organisms and a method for identifying a modulator or mediator of a biological activity, which activity includes antigenicity and/or immunogenicity, said method comprising the steps of: (i) producing a gene fragment expression library derived from defined nucleotide sequence fragments; and (ii) assaying the expression library for at least an amino acid sequence derived from step (i) for a biological activity wherein that act
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