SEQUENTIAL REPORTER ENZYME LUMINESCENCE (SRL) METHODS AND COMPOSITIONS FOR PRACTICING THE SAME

摘要

Sequential reporter enzyme luminescence (SRL) methods are provided. In the subject methods, the activity of a reporter enzyme is evaluated using a secondary reporter system that employs a product of a reporter enzyme mediated reaction as a luminescent substrate, e.g., luciferase substrate. Also provided are kits and other compositions that find use in practicing the subject methods.