METHOD OF ARRAYING CELLS AT SINGLE-CELL LEVEL INSIDE MICROFLUIDIC CHANNEL AND METHOD OF ANALYSING CELLS USING THE SAME, AND CELL ANALYSIS CHIP USED FOR CARRYING OUT THE SAME

摘要

Provided are a method of arraying cells at a single-cell level effectively, simply and economically, a method of analyzing cells using the same, and a cell analysis chip used for carrying out the same. To this end, a microfluidic channel having well structures is formed, and a cell solution containing cells is then introduced into the fluidic channel. Thereafter, the cell solution recedes in the microfluidic channel, thus providing a method of arraying cells in the well structures at a single-cell level, a method of analyzing cells using the same, and a cell analysis chip used for carrying out the same. With only very small amount of samples, it is possible to arraying the cells at a single-cell level very simply and economically without an additional apparatus or power. Accordingly, responsiveness such as response intensity of each cell upon an analysis reagent can be observed and the analysis can be made at a single-cell level. That is, it is possible to enhance the reliability of the cell analysis notably and improve the efficiency and accuracy of an individual cell analysis remarkably, so that these methods and cell analysis chip can be widely applied to the whole bio industries.