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BENZTROPINE COMPOUNDS AND USES THEREOF AS DOPAMINE UPTAKE INHIBITORS
BENZTROPINE COMPOUNDS AND USES THEREOF AS DOPAMINE UPTAKE INHIBITORS
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机译:苯并噻吩类化合物及其用作多巴胺的抑制剂
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摘要
Disclosed are benztropine analogs having the formula (I) in which Ar is a C6-C20 monocyclic aryl group or a C10-C20 bicyclic aryl group or a heteroaryl, heterocyclic, or arylheterocyclic group having 2 to 12 carbon atoms and one or more heteroatoms selected from the group consisting of N, O, S, P, and any combination thereof; m=1 to 5; n=1 to 3; and R1 to R4 are as described in the specification; or a pharmaceutically acceptable salt or solvate thereof; pharmaceutical compositions and use thereof, e.g., in treating mental disorders.
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机译:公开了具有式(I)的苯甲平类似物,其中Ar为C 6 -C 20单环芳基或C 10 -C 20双环芳基或具有2至12个碳原子和一个或多个所选杂原子的杂芳基,杂环或芳基杂环基选自N,O,S,P及其任何组合; m = 1至5; n = 1至3; R1至R4如说明书中所述;或其药学上可接受的盐或溶剂化物;药物组合物及其在例如治疗精神疾病中的用途。
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