首页> 外国专利> INJECTABLE PHOTO-CROSSLINKED HYDROGELS, BIODEGRADABLE IMPLANT AND DRUG DELIVERY SYSTEM USING THE SAME, AND THE PREPARATION METHOD THEREOF

INJECTABLE PHOTO-CROSSLINKED HYDROGELS, BIODEGRADABLE IMPLANT AND DRUG DELIVERY SYSTEM USING THE SAME, AND THE PREPARATION METHOD THEREOF

机译:可注射的光交联的水合物,使用其的可生物降解的植入物和药物输送系统及其制备方法

摘要

An injectable photo-crosslinked hydrogel, a biodegradable implant and a drug delivery system using the same, and a preparation method thereof are provided to form hydrogels safely on an injected part. A biodegradable implant using an injectable photo-crosslinked hydrogel includes the steps of: obtaining a polymer solution by dissolving biodegradable medical polymer and a photo-crosslinker in a solvent; injecting the polymer solution into a syringe; initiating photo-crosslinking by irradiating light to the polymer solution; and injecting the polymer solution into mammal except a human being with a syringe before the elastic strain becomes 20Pa or more. An effective amount of active components are additionally included in the polymer solution.
机译:提供了一种可注射的光交联水凝胶,可生物降解的植入物和使用其的药物递送系统及其制备方法,以在注射部位上安全地形成水凝胶。使用可注射的光交联的水凝胶的可生物降解的植入物包括以下步骤:通过将可生物降解的医用聚合物和光交联剂溶解在溶剂中来获得聚合物溶液;将聚合物溶液注入注射器中;通过向聚合物溶液照射光来引发光交联;在弹性应变变为20Pa以上之前,用注射器将聚合物溶液注入到除人以外的哺乳动物中。有效量的活性成分还包括在聚合物溶液中。

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