STRAIN STREPTOALLOTEICHUS CREMEUS SUBSP. TOBRAMYCINI PMBC-S1084-PRODUCER AND METHOD apramycin production of antibiotics apramycin sulphate

摘要

1. the strain Streptoalloteichus cremeus subsp.tobramycini wsc - S1084 - a producer u0430u043fu0440u0430u043cu0438u0446u0438u043du0430 antibiotics.;2. method u043fu043eu043bu0443u0447u0435u043du0438u00a0 antibiotics biosynthesis by strain - u043fu0440u043eu0434u0443u0446u0435u043du0442u0430, there on the u043au0430u0440u0431u043eu043au0441u0438u043bu044cu043du044bu0445 resins with subsequent u0434u0435u0441u043eu0440u0431u0446u0438u0435u0439 solutions of ammonia, u043eu0442u043bu0438u0447u0430u044eu0449u0438u0439u0441u00a0 order that, as u043fu0440u043eu0434u0443u0446u0435u043du0442u0430 using a mutant strain Streptoalloteichus cremeus subsp.tobramycini BKTIM - S1084 and u0430u043fu0440u0430u043cu0438u0446u0438u043d u0432u044bu0434u0435u043bu00a0u044eu0442 as sulphate there on u043au0430u0440u0431u043eu043au0441u0438u043bu044cu043du044bu0445 u043au0430u0442u0438u043eu043du0438u0442u0430u0445 followed by treatment with u0445u0440u043eu043cu0430u0442u043eu0433u0440u0430u0444u0438u0447u0435u0441u043au043eu0439 u0434u0432u0443u0445u043au043eu043bu043eu043du043eu0447u043du044bu043c method u0442u0443u043fu0435u043du0447u0430u0442u043eu0439 u044du043bu044eu0446u0438u0438 solutions (0.19 - 0.22). ammonia concentration in a vacuum and deposition in the form of sulphate.