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condensed heterocyclic compounds and their use as antagonists of the metabotropen reznkungen

机译:稠合杂环化合物及其作为美罗培南开放剂的拮抗剂的用途

摘要

The present invention is directed to compounds of formula: (I); wherein XSUP1/SUP, XSUP2/SUP, XSUP3/SUP, XSUP4/SUP, XSUP5/SUP, XSUP6/SUP, XSUP7/SUP, XSUP8/SUP, XSUP9/SUP, XSUP10/SUP, RSUP1/SUP, RSUP2/SUP, RSUP3/SUP, RSUP4/SUP, and n are as defined for formula I in the description. The invention also relates to processes for the preparation of the compounds and to new intermediates employed in the preparation, pharmaceutical compositions containing the compounds, and to the use of the compounds for treating gastrointestinal disorders.
机译:本发明涉及式:(I)的化合物;其中X 1 ,X 2 ,X 3 ,X 4 ,X 5 ,X 6 ,X 7 ,X 8 ,X 9 ,X 10 ,R 1 ,R 2 ,R 3 ,R 4 和n与上式中的式I定义相同说明。本发明还涉及化合物的制备方法和制备中使用的新的中间体,含有该化合物的药物组合物,以及该化合物在治疗胃肠道疾病中的用途。

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