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(2 hydroxy 3 oxo - shikuropento 1 eniru) the ester of acetic acid, (-) the R homo- citric acid gamma - lactone, (+) the S homo- citric acid gamma - lactone, and it corresponds (-) the R homo- citric acid salt (+) use of the ester in order to form the S homo- citric acid salt
(2 hydroxy 3 oxo - shikuropento 1 eniru) the ester of acetic acid, (-) the R homo- citric acid gamma - lactone, (+) the S homo- citric acid gamma - lactone, and it corresponds (-) the R homo- citric acid salt (+) use of the ester in order to form the S homo- citric acid salt
Archiral (2-hydroxy-3-oxo-cyclopent-1-enyl) acetic acid) alkyl, alkylphenyl and phenyl esters, and a simple and efficient method for the synthesis of both enantiomers of homocitric acid gamma-lactone and the corresponding salts from these esters are described. The method is based on asymmetric oxidation of esters, and the steps of basic and acidic hydrolysis and final acidic lactonization of the homocitric acid into homocitric acid gamma-lactone. The homocitric acid salts are obtained after basic treatment of homocitric acid gamma-lactone. The esters, conditions and reagents used in chemical conversion and separating products are important constituents affording efficient and simple method for production of homocitric acid gamma-lactone and homocitric acid salts.
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