首页> 外国专利> NEW BIOMARKER FOR DIFFERENTIAL DIAGNOSIS OF CHRONIC HEPATITIS, CIRRHOSIS, HEPATOMA AND DIFFERENTIAL DIAGNOSIS METHOD FOR CHRONIC HEPATITIS, CIRRHOSIS, HEPATOMA USING BIOMARKER

NEW BIOMARKER FOR DIFFERENTIAL DIAGNOSIS OF CHRONIC HEPATITIS, CIRRHOSIS, HEPATOMA AND DIFFERENTIAL DIAGNOSIS METHOD FOR CHRONIC HEPATITIS, CIRRHOSIS, HEPATOMA USING BIOMARKER

机译:慢性肝炎,肝硬化,肝炎鉴别诊断的新生物标记和使用生物标记物的慢性肝炎,肝硬化,肝炎鉴别诊断的方法

摘要

PROBLEM TO BE SOLVED: To provide a method for detecting chronic hepatitis, cirrhosis, hepatoma with a protein whose presence or absence and whose amounts are different between normal persons and patients of chronic hepatitis, cirrhosis, hepatoma and its partial peptide, and to provide a biomarker comprising the protein and its partial peptide and used for the differential diagnosis of the chronic hepatitis, cirrhosis, hepatoma.;SOLUTION: The present invention relates to the biomarker which includes at least one protein selected from the group consisting of specific proteins and the group consisting of partial peptides comprising amino acid sequences that are the partial peptides of the proteins, or a peptide fragment produced from the protein and having five or more amino acid residues, and are used for the differential diagnosis of the chronic hepatitis, cirrhosis, hepatoma, to a differential diagnosis method, and to an antigen peptide for making a peptide specific antibody used for the specific differential diagnosis method.;COPYRIGHT: (C)2009,JPO&INPIT
机译:要解决的问题:提供一种检测慢性肝炎,肝硬化,肝癌的方法,该蛋白质的存在与否以及正常人与慢性肝炎,肝硬化,肝癌及其部分肽段患者之间的含量不同。包含蛋白质及其部分肽的生物标志物,用于鉴别诊断慢性肝炎,肝硬化,肝癌。解决方案:本发明涉及一种生物标志物,其包括至少一种选自以下的蛋白质:特异性蛋白质和由部分肽组成,该部分肽包含作为蛋白部分肽的氨基酸序列,或由该蛋白产生并具有五个或多个氨基酸残基的肽片段,用于慢性肝炎,肝硬化,肝癌的鉴别诊断,鉴别诊断方法,以及用于制备用于t的肽特异性抗体的抗原肽具体的鉴别诊断方法。版权所有:(C)2009,JPO&INPIT

著录项

  • 公开/公告号JP2009114092A

    专利类型

  • 公开/公告日2009-05-28

    原文格式PDF

  • 申请/专利权人 MCBI:KK;

    申请/专利号JP20070286461

  • 申请日2007-11-02

  • 分类号C07K14/47;C07K16/18;G01N33/53;G01N33/536;G01N33/574;G01N33/576;G01N27/62;C12Q1/04;C12N15;

  • 国家 JP

  • 入库时间 2022-08-21 19:43:01

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