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Inducing Premature Senescence to Stabilize Stem Cell Feeder Layer Cells
Inducing Premature Senescence to Stabilize Stem Cell Feeder Layer Cells
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机译:诱导过早衰老稳定干细胞饲养层细胞。
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摘要
The present invention provides stem cell feeder layer cell lines that contain are readily triggered to differentiation. The expression vector encodes the senescence-triggering factors (STFs) consisting of Cip/Kip, INK4A, Cy protein or ankyrin-binding protein motifs. Each expression vector also contains an inducible transcription regulation element for conditional expression of the STFs.
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