Isolated nucleic acid; vector; host cell; Method for expressing a protein; isolated polypeptide; isolated chromoprotein; oligonucleotide; Method for identifying a Nucleic Acid encoding a chromoprotein-containing nine-membered enediine apoprotein; biologically pure culture of actinomadura sp. 21g792 (nos. 30778); Method for preparing a chromoprotein; Method for preparing a modified chromoprotein; Method for inhibiting the progression of a neoplastic disease in a mammal; pharmaceutical composition; it's composed

摘要

NUCLEIC ACID ISOLATED; VECTOR; HOST CELL; Method for expressing a protein; ISOLATED POLYPEPTIDE; Isolated chromoprotein; OLIGONUCLEOTIDE; METHOD FOR IDENTIFYING NUCLEIC ACID ENCODING AN APPROPRIATE OF NINE MEMBERS CONTAINING CHROMOPROTEIN; BIOLOGICALLY PURE CULTURE OF ACTINOMADURA SP. 21G792 (NRRL 30778); Method for preparing a chromoprotein; Method for preparing a modified chromoprotein; METHOD FOR INHIBITING THE PROGRESS OF A NEOPLASIC DISEASE IN A MAMMER; PHARMACEUTICAL COMPOSITION; IT'S COMPOSED. The present invention relates to a chromoprotein produced by Actinomadura sp. 21G792, as well as amino acid and nucleic acid sequences of the chromoprotein apoprotein component and chromophore biosynthetic pathway components. The present invention is useful for developing pharmaceutical compositions and treating diseases such as cancer or bacterial infections.